NAD+ Decline: Why Supplementation Matters NAD+ is a critical coenzyme in hundreds of cellular processes, including energy production (glycolysis, citric acid cycle, oxidative phosphorylation), DNA repair through PARP activation, sirtuin-mediated...
“These data from a community-based sample demonstrate that SWS percentage declines over time in adults 60 years and older and that greater declines are associated with the risk of future...
This study showed that Quercetin protected rats with osteoarthritis against bone and cartilage damage by reducing inflammation and modulating levels of proteins associated with cartilage health.
This study showed that NR supplementation protected mice from HFD-induced metabolic dysfunction, specifically through protecting mitochondrial function in the skeletal muscle.
Use of NMN supplements was shown to activate Sirtuin-1, one of the body’s self repair enzymes, to repair kidney damage and restore kidney function in mice. (1)
Doubling Slc128a Dramatically Improved Muscle Strength and Endurance It’s known that NMN transporters like Slc128a help to maintain NAD+ levels as we age. This caused researchers to speculate what may...