Key Points Increased median lifespan by 8.5% in female mice. Reduced frailty observed in both male and female mice. Enhanced metabolic health, particularly in male mice. Altered gut microbiome with...
Nicotinamide Riboside (NR) shown to increase lifespan of mice by 25% Only two compounds in this study were shown to have an effect on lifespan in mice engineered to age...
NMN and NR lead to greater increases in NAD+ than NAM It has been well established that the molecules NMN and NR lead to greater increases in NAD+ levels than...
Since immune cells play such a critical role in keeping the population of senescent cells in check, senescent immune cells are a prime target of senolytic drugs. Fisetin has been...
As we age, the risk for clogged arteries, brittle blood vessels, and heart failure increase. A recent study looking at the DNA in numerous individual heart cells tells the story...