Scientific Evidence Library

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Scientific Evidence Library

article-page-carousel-item--NMN Reduces Heart Failure and Extends Lifespan in Mice

NMN Reduces Heart Failure and Extends Life...

3 min

“These results suggest that NMN treatment functionally ameliorated or prevented exacerbation of heart failure in p32 cardiomyocyte–specific knockout mice, thereby prolonging their lifespan.”

3 min

NMN Reduces Heart Failure and Extends Lifespan ...

“These results suggest that NMN treatment functionally ameliorated or prevented exacerbation of heart failure in p32...

article-page-carousel-item--NMN Improves Blood Pressure in Humans with Hypertension

NMN Improves Blood Pressure in Humans with...

5 min

“Overall, the present study may shed new light on novel strategies in which NAD+ boosting therapy, including NMN supplement and CD38 inhibition, may turn out to be a promising therapeutic...

5 min

NMN Improves Blood Pressure in Humans with Hype...

“Overall, the present study may shed new light on novel strategies in which NAD+ boosting therapy,...

article-page-carousel-item--Study Reveals New Technique to Quickly and Accurately Measure Blood NAD+ Levels

Study Reveals New Technique to Quickly and...

5 min

Highlights A new technique has been developed to rapidly and effectively measure blood NAD+ levels in humans. Aerobic exercise and NMN supplementation increase NAD+ levels Gender- and age- variations in...

5 min

Study Reveals New Technique to Quickly and Accu...

Highlights A new technique has been developed to rapidly and effectively measure blood NAD+ levels in...

Anti-Aging Effects of NMN - Human Clinical...

6 min

Resveratrol supplementation effectively protected mice against age-related muscle mass loss, heart cell enlargement, and motor dysfunction.

6 min

Anti-Aging Effects of NMN - Human Clinical Tria...

Resveratrol supplementation effectively protected mice against age-related muscle mass loss, heart cell enlargement, and motor dysfunction.

article-page-carousel-item--Study Shows NR Injections Increase Muscle NAD+ in Mice, Oral Supplementation Does Not

Study Shows NR Injections Increase Muscle ...

2 min

NR injections boosted NAD+ levels in skeletal muscle and white adipose tissue. A ~140% increase in muscle NAD+ was observed after 7 days of IV administration of NR. Oral administration...

2 min

Study Shows NR Injections Increase Muscle NAD+ ...

NR injections boosted NAD+ levels in skeletal muscle and white adipose tissue. A ~140% increase in...

article-page-carousel-item--NMN Human Trial Shows Increased Endurance, NAD+ Blood Levels, and Benefits to Bioage

NMN Human Trial Shows Increased Endurance,...

3 min

Study set out to determine safety and efficacy of NMN supplementation in 4 groups NAD+ levels are known to decline with age, affecting longevity and age-related health conditions, better known...

3 min

NMN Human Trial Shows Increased Endurance, NAD+...

Study set out to determine safety and efficacy of NMN supplementation in 4 groups NAD+ levels...

article-page-carousel-item--NAD Precursors Cycle Between Host Tissues and the Gut Microbiome

NAD Precursors Cycle Between Host Tissues ...

2 min

Thus, circulating host NAM enters the gut lumen and is used by the microbiome for both NAD and NA synthesis. Thus, gut microbiota provide an alternative route from NAM to...

2 min

NAD Precursors Cycle Between Host Tissues and t...

Thus, circulating host NAM enters the gut lumen and is used by the microbiome for both...

article-page-carousel-item--Dogs and Humans Share Same Benefits from NMN Supplementation

Dogs and Humans Share Same Benefits from N...

2 min

Dog and human NAD+ levels both decline with age Dogs have the same problem as humans in that their NAD+ levels decline with age in various critical organs, such as...

2 min

Dogs and Humans Share Same Benefits from NMN Su...

Dog and human NAD+ levels both decline with age Dogs have the same problem as humans...

article-page-carousel-item--NMN and Resveratrol Work Synergistically to boost NAD+ in Heart and Skeletal Muscle

NMN and Resveratrol Work Synergistically t...

2 min

A new study shows that the combination of NMN and Resveratrol works synergistically to increase NAD+ levels in both heart and skeletal muscle tissues in mice. Combination treatments shown to...

2 min

NMN and Resveratrol Work Synergistically to boo...

A new study shows that the combination of NMN and Resveratrol works synergistically to increase NAD+...

article-page-carousel-item--NAD+ Reduces Mutations and Incidence of Skin Cancer

NAD+ Reduces Mutations and Incidence of Sk...

3 min

NMN and NR lead to greater increases in NAD+ than NAM It has been well established that the molecules NMN and NR lead to greater increases in NAD+ levels than...

3 min

NAD+ Reduces Mutations and Incidence of Skin Ca...

NMN and NR lead to greater increases in NAD+ than NAM It has been well established...

article-page-carousel-item--Inhibition of CD38 Increases NAD+ Levels

Inhibition of CD38 Increases NAD+ Levels

3 min

Inhibition of CD38 Increases NAD+ and Extends Lifespan and Healthspan Two recent studies have found that inhibition of CD38 (with 78c or PCC1) increase NAD+ levels and result in significant...

3 min

Inhibition of CD38 Increases NAD+ Levels

Inhibition of CD38 Increases NAD+ and Extends Lifespan and Healthspan Two recent studies have found that...

article-page-carousel-item--NMN Triples NAD+ Levels in Humans

NMN Triples NAD+ Levels in Humans

3 min

NMN doses of 1,000 mg taken once daily doubles NAD+ levels (middle graph). When taken twice daily, NMN triples NAD+ levels (right graph). Dr. David Sinclair is a co-founder of...

3 min

NMN Triples NAD+ Levels in Humans

NMN doses of 1,000 mg taken once daily doubles NAD+ levels (middle graph). When taken twice...