Key Points Increased median lifespan by 8.5% in female mice. Reduced frailty observed in both male and female mice. Enhanced metabolic health, particularly in male mice. Altered gut microbiome with...
Study set out to determine safety and efficacy of NMN supplementation in 4 groups NAD+ levels are known to decline with age, affecting longevity and age-related health conditions, better known...
Dog and human NAD+ levels both decline with age Dogs have the same problem as humans in that their NAD+ levels decline with age in various critical organs, such as...
Use of NMN supplements was shown to activate Sirtuin-1, one of the bodyβs self repair enzymes, to repair kidney damage and restore kidney function in mice. (1)
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Doubling Slc128a Dramatically Improved Muscle Strength and Endurance Itβs known that NMN transporters like Slc128a help to maintain NAD+ levels as we age. This caused researchers to speculate what may...
As we age, the risk for clogged arteries, brittle blood vessels, and heart failure increase. A recent study looking at the DNA in numerous individual heart cells tells the story...
Two recent studies have found that inhibition of CD38 (with 78c or PCC1) increase NAD+ levels and result in significant increases in lifespan and healthspan in mice.
Resveratrol is a polyphenol derived from plants with antioxidant properties that have been shown to enhance the activation of the body's own self-repair proteins, called sirtuins. When sirtuins are activated,...
These improvements in health and behavior persisted for the length of the study, which was 90 days after birth. Some quotes from the study: Adding NR to normal chow (NC)...