1.7 Ounces Per Bottle

Recommended 2 Pumps

Liposomal Face Serum

Renue Blue™ Face Serum

Name: Renue Blue™ Face Serum with Methylene Blue, Glutathione, NAD⁺, NMN, NR (Liposomal)
Brand: Renue Store
SKU: 656165996537
Price: 467.0 CNY
Availability: InStock

Powerful skin rejuvenation

¥467.00 CNY

Shipping calculated at checkout.

Renue Blue Face Serum formula has FOUR TIMES the amount of Methylene Blue, along with liposomal NAD+, NMN, NR, Apocynin, Glutathione and ALA.

Provides absorption across the layers of the skin using breakthrough nanoliposome technology. Use alone or as the first step in the 2-part complete Renue Blue Skincare Protocol.

Product variants

1.7 Ounces Per Bottle

Recommended 2 Pumps

Liposomal Face Serum

Details

Renue Blue™ Face & Hand Serum

Renue Blue Face & Hand Serum works at the cellular level to deliver time-released actives that restore NAD⁺ to improve skin’s texture, firmness, and dermal matrix.

The epitome of science and performance, Renue Blue Face & Hand Serum works renews cells from within using a proprietary Liposomal Methylene Blue with NAD⁺ Complex (NAD⁺, NMN, and NR)—science-backed nutrients that provide nourishment on the cellular level.

Renue Blue works at the cellular level to deliver time-released actives that restore NAD⁺ to improve skin’s texture, firmness, and dermal matrix.

Nano-sized liposomes penetrate quickly and deeply into dermal layers to deliver a very high concentration of active ingredients that provide unique therapeutic benefits over all other serums.

Expertly formulated with liposomal NAD⁺ Complex (NAD⁺, NMN, and NR) and Methylene Blue, along with Apocynin, and Glutathione, this potent delivery system offers a deeper penetration of key ingredients into the skin’s surface to combat the most visible signs of aging and promote vibrant, youthful-looking skin.

Use day and night with Renue Blue Face Creme. Suitable for all skin types.

Can be used alone, or as the first step in the 2-part complete Blue Skincare Protocol, before using the Blue Cream for maximum effectiveness.

LIPOSOMAL NAD⁺ COMPLEX

NAD⁺ Complex is a powerful trio, containing NAD⁺, NMN and NR. As you age, your skin requires higher levels of NAD⁺ to combat damage and keep your skin in a youthful and healthy state. Aging is directly associated with lower NAD⁺ levels in the skin. Delivery of NAD⁺ and NAD⁺ boosters through liposomal skincare is the optimal way to safely raise levels of NAD⁺ in the skin.

METHYLENE BLUE

Methylene Blue has been studied for a wide range of ailments, many of which are aging-related illnesses, and there are currently over 20,000 studies on Pubmed.One studyconducted at the University of Maryland tested the potential dermal anti-aging benefits of four antioxidants, one of which was Methylene Blue.

Among all of the antioxidants studied, Methylene Blue was by far, the most effective.

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Renue Blue™ Skincare

Renue Blue works at the cellular level to deliver time-released active ingredients that restore NAD⁺ to improve skin’s texture, firmness, and dermal matrix.

The epitome of science and performance, Renue Blue renews cells from within using a proprietary form of Liposomal Methylene Blue with NAD⁺ Complex (NAD⁺, NMN, and NR), Apocynin, Glutathione, Hyaluronic Acid, and other potent science-backed nutrients that provide nourishment on the cellular level.

Nano-sized liposomes penetrate quickly and deeply into dermal layers to deliver a very high concentration of active ingredients that provide unique therapeutic benefits over all other skincare methods.

This potent delivery system offers a deeper penetration of key ingredients into the skin’s surface to combat the most visible signs of aging and promote vibrant, youthful-looking skin.

LIPOSOMAL NAD⁺ COMPLEX

METHYLENE BLUE

Methylene Blue has been studied for a wide range of ailments, many of which are aging-related illnesses, and there are currently over 20,000 studies on Pubmed. One study conducted at the University of Maryland tested the potential dermal anti-aging benefits of four antioxidants, one of which was Methylene Blue.

Among all of the antioxidants studied, Methylene Blue was by far, the most effective.

University of Maryland Study

The study was conducted by the Department of Cell Biology & Molecular Genetics, at the University of Maryland.In the study, researchers tested out four antioxidants on the skin, one of which was Methylene Blue. The second one was N. Acetyl Cysteine, or NAC, a very popular antioxidant, often taken as a supplement. The last two were MitoQ and mTEM - both of which are mitochondrial targeting antioxidants.They applied each one topically to skin fibroblasts of healthy middle-aged adults, adults 80 and older and from people with progeria.For most studies, skin fibroblasts are obtained through a non-invasive procedure that involves numbing at the site and taking a punch skin biopsy sample.

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RENUE™ - 2 Step Skin Rejuvenation Protocol

Step 1

Renue Serum is Quickly Absorbed

Serums are made of very small molecules that penetrate your skin faster and more effectively, carrying the active ingredients to deeper layers and into systemic circulation.

Apply serum first for penetration to deepest skin layers and systemic circulation.

Allow to soak in for 1-2 minutes.

Step 2

Renue Lotion Protects Surface Layer

The thicker, more emollient ingredients in our Face Cream concentrate more active ingredients in the surface layer.

Apply Renue Face Cream for additional nutrient delivery, skin protection, and moisturization.

The 2-part protocol can be used as a complete skincare system or used under cosmetics.

Active Liposomal Ingredients

Methylene Blue
NAD⁺ Complex: Nicotinamide Adenine Dinucleotide (NAD⁺) · Nicotinamide Mononucleotide (NMN)
Apocynin
Glutathione
Alpha-Lipoic Acid (ALA)
Hyaluronic Acid (HLA)

Helianthus Annuus (from Sunflower Lecithin) · Glycerin · Aloe Barbadensis (Aloe Vera) · Rosmarinus Officinalis · Chondrus Crispus (Seaweed Extract) · Hyaluronic Acid (HLA) · Alpha-Lipoic Acid (ALA) · Citric Acid

Emollients & Stabilizers

Tocopherols (Vitamin E) · Propylene Glycol · Carbomer · Cetearyl Alcohol · Glycerol Stearate · Triethanolamine · Potassium Sorbate

Active Liposomal Ingredients

Methylene Blue
NAD⁺ Complex: Nicotinamide Adenine Dinucleotide (NAD⁺) · Nicotinamide Mononucleotide (NMN)
Apocynin
Glutathione
Alpha-Lipoic Acid (ALA)
Hyaluronic Acid (HLA)

Emollients & Stabilizers

Tocopherols (Vitamin E) · Propylene Glycol · Carbomer · Cetearyl Alcohol · Glycerol Stearate · Triethanolamine · Potassium Sorbate

Renue Blue Skin Rejuvenation Protocol

The two-part system combines the latest advancements in skincare science to deliver unrivaled anti-aging benefits. This innovative protocol includes the Renue Blue Serum (Step 1) and the Renue Blue Cream (Step 2).

The Renue Blue Skin Rejuvenation Protocol is formulated around the NAD+ Complex and Methylene Blue, supported by other scientifically proven nutrients to improve skin’s smoothness, elasticity, and strength.

The NAD+ Complex, a powerful blend of NAD+, NMN, and NR. As we age, NAD+ levels in our skin naturally decline, contributing to the visible signs of aging such as thinning, wrinkling, and uneven skin tone.

Renue Blue Skin Rejuvenation Protocol

article-page-carousel-item--The Liposome Advantage

Resveratrol

“The Longevity Molecule”

Resveratrol is a stilbenoid polyphenol synthesized by plants in response to stressful stimuli and is protective in aging. 9, 10, 6Its broad-spectrum properties (antimicrobial, anti-inflammatory, antioxidant and anti-aging) make it a potent bioactive for dermatological application by limiting the effects of cellular aging. 11Its antioxidant activity (95%) is higher than vitamin E (65%) and C (37%) and has been shown to be active in neutralizing and inhibiting the formation of reactive oxygen species. 6, 12

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Resveratrol

“The Longevity Molecule”

Resveratrol is a stilbenoid polyphenol synthesized by plants in response to stressful stimuli and is protective in aging. 9, 10, 6

Its broad-spectrum properties (antimicrobial, anti-inflammatory, antioxidant and anti-aging) make it a potent bioactive for dermatological application by limiting the effects of cellular aging. 11

Its antioxidant activity (95%) is higher than vitamin E (65%) and C (37%) and has been shown to be active in neutralizing and inhibiting the formation of reactive oxygen species. 6, 12

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Apocynin

“The Skin Cell Tonic”

Apocynin, a natural vanilloid compound, has emerged as a bioactive phytochemical with potent anti-inflammatory properties for the skin. 13A new paper published in Nature, found that declining levels of a collagen protein called COL17A1 (Collagen 17), cause our skin to develop wrinkles, sag and lose elasticity. 4Apocynin was able to restore levels of Collagen 17 and repair damaged skin, leading scientists to believe it’s possible to reverse our skin’s timeline at the cellular level. 14

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Apocynin

“The Skin Cell Tonic”

Apocynin, a natural vanilloid compound, has emerged as a bioactive phytochemical with potent anti-inflammatory properties for the skin. 13

A new paper published in Nature, found that declining levels of a collagen protein called COL17A1 (Collagen 17), cause our skin to develop wrinkles, sag and lose elasticity. 4

Apocynin was able to restore levels of Collagen 17 and repair damaged skin, leading scientists to believe it’s possible to reverse our skin’s timeline at the cellular level. 14

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NAD⁺

"The Youth Molecule"

May Improve RosaceaAccording to research Topical NAD⁺ has been shown to improve metabolism of skin cells. Its profound antioxidant properties can lessen inflammation that is associated with the damaging effects of free radicals.May Improve PsoriasisAccording to this study, it’s as effective as the leading pharmaceutical at treating psoriasis, and without side effects. NAD⁺ mitigates cellular damage and lessens inflammation, which leads to a visible improvement in the skin.

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NAD⁺

"The Youth Molecule"

May Improve Rosacea

According to research Topical NAD⁺ has been shown to improve metabolism of skin cells. Its profound antioxidant properties can lessen inflammation that is associated with the damaging effects of free radicals.

May Improve Psoriasis

According to this study, it’s as effective as the leading pharmaceutical at treating psoriasis, and without side effects. NAD⁺ mitigates cellular damage and lessens inflammation, which leads to a visible improvement in the skin.

Learn more

Frequently Asked Questions

Skincare

What is the difference between the face and body serums?

The Body Serum contains vitamin D to increase levels of vitamin D in the body and can also be applied to the face. The Face Serum contains a concentrated form of Vitamin C to neutralize free radicals from external factors like air pollution and sunlight. The Face Serum can also be applied to the body, if desired.

Can I use Renue Blue skincare products with retinol or tretinoin?

Many of our customers use them both. It is safe to use the methylene blue skincare in conjunction with a retinol cream. The methylene blue skincare products are not harsh or irritating in the way that retinol creams may be for some people.For the best results, you could apply the methylene blue skincare in the morning and the retinol cream at night. That way your skin is receiving a nice dose of antioxidants in the morning and throughout the day, then at night you're doing your retinol treatment.Retinol and methylene blue skincare products both work to improve and increase cellular proliferation - creating new healthier cells. Using retinol at night can help speed up cellular turnover, and by using the methylene blue skincare in the morning, it has more of a healing and protective effect on the skin. So, they work really well together.

What are the benefits of liposomal delivery? Are liposomes really better?

When taken sublingually, approximately 30% of a 125 mg dose gets absorbed under the tongue, with the remainder being swallowed. At higher dosages, the % goes down, as the capillaries are full and have limited transport.

A much greater % makes it to bloodstream with liposomal delivery. Liposomes also protect the payload from degradation once in the bloodstream.

Lastly, Liposomes release the payload over a much longer period – up to 24 hours. This is better when taking larger dosages.

The rapid delivery to the bloodstream with Sublingual can be an advantage when taking before exercise. The energy surge most users feel is also nice confirmation that it is doing something.

What are the liquid and powdered liposome differences in bioavailability and stability?

Our liquid and powdered liposomes have approximately the same availability in the bloodstream, but the powdered liposomes release the payload more slowly over 24 hours. We don’t know if that makes it more effective than a faster release.

Powdered liposomal products have a shelf life of over two years, rather than the 12 months or so for liquid liposomal products when stored at room temp.

What's the difference between Liposomal vs. Delayed & Extended Release Caps?

Delayed Release & Extended Release Caps protect ingredients from stomach acid only. They delay, but don't really sustain ingredient release.

Liposomes protect the payload through the GI tract and into the bloodstream, then release more slowly up to 24 hours (depending on the liposome).

In addition to a big increase in bioavailability, they are truly sustained release. Any supplement known to have poor bioavailability should use liposomal delivery.

Are any of your liposomal products heat-sensitive?

The liposomal powder capsule products are not heat sensitive.

The liposomal gels however should not be exposed to heat exceeding 115 degrees Fahrenheit for more than a few days. Liposomes break down a bit when exposed to extended periods of high heat.

Skincare

Are any of your liposomal products heat-sensitive?

"I have a skincare product that I am really loving right now & it's a mix between a skincare product & a supplement." - Claudia Glows (Length: 7:37)

"This will really help maintain your levels of collagen." - Madison (Length: 4:38)

"It feels like I'm putting liquid gold on my arm." - Madison (Length: 4:40)

"I wish I could take a bath in it." - Claudia Glows (Length: 3:25)

"I'm amazed at the difference I'm seeing." - Claudia Glows (Length: 2:35)

"Overall, this is a powerhouse of ingredients!" - Claudia Glows (Length: 4:13)

Trial Results

Our Renue NAD⁺ Lotion was first introduced in May of 2019 and we've received great feedback on it. Our skincare line has since expanded and we are even more excited about the potential of our face Serum for restoring and supporting skin health through aging.

We decided to perform our own little trial, and sent out an email to our customer base asking for volunteers that would allow use to use their before and after images in exchange for free product to test. The first 100 people to reply were accepted and were shipped the first bottle of serum just before Thanksgiving 2020.

We were pleased to find that after 30 days, all of the 100 subjects wanted to continue use, and gave us feedback on what they experienced. The overwhelming majority was extremely positive!

Of course these results are mostly subjective and not proof of anything, but we are very encouraged by them, and believe we will be getting a lot of good before/after images like the ones below.

before & after photos

Smoother Skin & Sun Damage Diminished

“I applied the serum and day cream to my face after washing it every morning, and before applying my regular SPF moisturizer, and noticed a difference on my skin about 2 months after I started using it. My skin looks brighter, and some sun spots have definitely gotten lighter. I also noticed that the texture of my skin feels like it has more elasticity to it. I love that the products are very light, and absorb quickly. I can’t wait to see the results after using it for longer.”

- Alexia, Age 38

Learn More About Liposomal Delivery

Liposomes are a revolutionary way of encapsulating active ingredients in a phospholipid “bubble” to protect and deliver them directly to the cells of your tissues, which are reached via the bloodstream.⑴

This allows for the ingredients to be absorbed and utilized rather than being destroyed in the stomach.

The aim of taking any supplement is to ensure its transport into the bloodstream. However, due to the low absorption and bioavailability rates of traditional oral capsules, active ingredients lose most of their potency while passing through the gastrointestinal tract or are simply not absorbed in the small intestine at all. The majority is excreted unused via the intestines or kidneys. ⑵

Liposomal delivery offers a targeted and complete absorption of active ingredients with a delayed‑release effect, unlike all other nutrient delivery methods. This increased circulation time of key nutrients in the bloodstream significantly improves bioavailability. The higher the bioavailability of an active substance, the more effect it has on the body.

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Certifications

Supported by Science

Purest Ingredients

All our products are non-GMO and 100% free from preservatives, artificial colours, flavours and sweeteners.

Advanced Testing

We use pharmaceutical-grade testing procedures and our products have to pass through 4 rounds of testing.

Certified Labs

Our products are tested in ISO-Certified and cGMP certified labs for ultimate quality, purity and potency.