Research

CD73 utilization shows importance of NMN to res...
Like prior studies (1), they found that this transport method did not impede NMN from entering cells, as NR and NMN performed equally at restoring NAD+. They also determined that...
CD73 utilization shows importance of NMN to res...
Like prior studies (1), they found that this transport method did not impede NMN from entering...

Case Study on Liposomal NMN Shows Positive Impa...
“In an animal model of type 2 diabetes, the intragastric delivery of Lip-BBR via liposomes exhibited remarkable protective effects against hepatic tissue damage, steatosis, inflammation, insulin resistance, and hepatocellular enzyme...
Case Study on Liposomal NMN Shows Positive Impa...
“In an animal model of type 2 diabetes, the intragastric delivery of Lip-BBR via liposomes exhibited...

How NAD+ Boosts ATP and What it Means for Healt...
Declining ATP as we age Adenosine triphosphate (ATP) is the main biological fuel used by our body. It provides every cell with energy for the essential processes such as muscle...
How NAD+ Boosts ATP and What it Means for Healt...
Declining ATP as we age Adenosine triphosphate (ATP) is the main biological fuel used by our...

1st NMN Human Study Demonstrates Safety and Fas...
The single oral administration of NMN was safe and effectively metabolized in healthy men without causing any significant deleterious effects. Thus, the oral administration of NMN was found to be...
1st NMN Human Study Demonstrates Safety and Fas...
The single oral administration of NMN was safe and effectively metabolized in healthy men without causing...

NAD+ IV increases NAD+ levels in blood plasma 4...
In summary, this study revealed for the first time that: (a) at a flow rate of 3 μmole/min all exogenously infused NAD+ was rapidly and completely removed from the plasma...
NAD+ IV increases NAD+ levels in blood plasma 4...
In summary, this study revealed for the first time that: (a) at a flow rate of...

NAD+ is the Transport Molecule Used by the Body...
The benefits noted from supplementation with NR in recent research are from increased NAD+ circulating in the bloodstream, not NR. Sublingual NAD+ or NMN are likely much more efficient methods...
NAD+ is the Transport Molecule Used by the Body...
The benefits noted from supplementation with NR in recent research are from increased NAD+ circulating in...

Slc12a8 Does not Solve the Bioavailability Prob...
This research was published in January 2019 that found an enzyme named Slc12a8 that can transport a small quantity of Nicotinamide Mononucleotide (NMN) directly into some cells.
Slc12a8 Does not Solve the Bioavailability Prob...
This research was published in January 2019 that found an enzyme named Slc12a8 that can transport...

Increased NAD+ in Bloodstream of Nursing Mice R...
These improvements in health and behavior persisted for the length of the study, which was 90 days after birth. Some quotes from the study: Adding NR to normal chow (NC)...
Increased NAD+ in Bloodstream of Nursing Mice R...
These improvements in health and behavior persisted for the length of the study, which was 90...

Scientists discover SLC12a8 pathway used by NMN...
More details about the research Slc12a8 in the small intestine is important for transporting NMN from the gut into the circulation, affecting NAD+ levels in the small intestine and the...
Scientists discover SLC12a8 pathway used by NMN...
More details about the research Slc12a8 in the small intestine is important for transporting NMN from...

NAD+ Supplements Regulate Energy Metabolism via...
This study shows that administration of 1 mg/kg of LABELED NAD+ crosses the blood brain barrier to enter the hypothalamus INTACT, increases NAD+ levels, reduces hunger and weight gain, and...
NAD+ Supplements Regulate Energy Metabolism via...
This study shows that administration of 1 mg/kg of LABELED NAD+ crosses the blood brain barrier...

Exogenous NAD+ Increases Metabolism
In a study published in 2018, scientists gave obese mice 1 mg/kg of NAD+ by inter peritoneal injection for 4 weeks, which restored NAD+ levels in the hypothalamus to normal...
Exogenous NAD+ Increases Metabolism
In a study published in 2018, scientists gave obese mice 1 mg/kg of NAD+ by inter...

What is NAD+?
NAD+ is a key co-enzyme that the mitochondria in every cell of our bodies depend on to fuel all basic functions. (3,4) NAD+ play a key role in communicating between...
What is NAD+?
NAD+ is a key co-enzyme that the mitochondria in every cell of our bodies depend on...