Research
NMN Triples NAD+ Levels in Humans
(Pencina et al., 2022 | The Journals of Gerontology) NMN doses of 1,000 mg taken once daily doubles NAD+ levels (middle graph). When taken twice daily, NMN triples NAD+ levels...
NMN Triples NAD+ Levels in Humans
(Pencina et al., 2022 | The Journals of Gerontology) NMN doses of 1,000 mg taken once...
NMN Triples NAD+ Levels in Humans
NMN doses of 1,000 mg taken once daily doubles NAD+ levels (middle graph). When taken twice daily, NMN triples NAD+ levels (right graph). Dr. David Sinclair is a co-founder of...
NMN Triples NAD+ Levels in Humans
NMN doses of 1,000 mg taken once daily doubles NAD+ levels (middle graph). When taken twice...
Why Dr. Sinclair takes NMN instead of NR
There has been little, if any, head to head research published comparing Nicotinamide Mononucleotide (NMN) and Nicotinamide Riboside (NR). However, Dr. Sinclair recently said he takes NMN instead of NR...
Why Dr. Sinclair takes NMN instead of NR
There has been little, if any, head to head research published comparing Nicotinamide Mononucleotide (NMN) and...
Why Dr. Sinclair takes NMN instead of NR
There has been little, if any, head to head research published comparing Nicotinamide Mononucleotide (NMN) and Nicotinamide Riboside (NR). However, Dr. Sinclair recently said he takes NMN instead of NR...
Why Dr. Sinclair takes NMN instead of NR
There has been little, if any, head to head research published comparing Nicotinamide Mononucleotide (NMN) and...
Lower Inflammation to Raise NAD+
Results from hundreds of tests for Intracellular NAD+ levels tell us that those with high inflammation levels (measured by HS-CRP) have less success raising NAD+ levels.Lowering inflammation can help restore...
Lower Inflammation to Raise NAD+
Results from hundreds of tests for Intracellular NAD+ levels tell us that those with high inflammation...
David Sinclair's Supplement Stack and Longevity...
David Sinclair, a professor at Harvard University is perhaps the foremost expert in the growing field of longevity research. In a recent video, titled “Dr David Sinclair – Defeating Ageing...
David Sinclair's Supplement Stack and Longevity...
David Sinclair, a professor at Harvard University is perhaps the foremost expert in the growing field...
NAD+ and the Hallmarks of Aging Series – Part 8...
Altogether, these studies suggest that the decline of stem cell number and function is a hallmark of aging and is a major cause of decreased tissue homeostasis in the old...
NAD+ and the Hallmarks of Aging Series – Part 8...
Altogether, these studies suggest that the decline of stem cell number and function is a hallmark...
Trimethylglycine (TMG) for Restoring Methylatio...
TMG is a critical cofactor in methylation, which occurs in every mammalian cell donating methyl groups. This includes the synthesis of neurotransmitters such as serotonin and dopamine.
Trimethylglycine (TMG) for Restoring Methylatio...
TMG is a critical cofactor in methylation, which occurs in every mammalian cell donating methyl groups....
NAD+ and the Hallmarks of Aging Series - Part 6...
These findings suggest that a conserved pathway may operate in mammals during calorie restriction involving the activation of SIRT1 and increased NAD+ that triggers an increase in mitochondrial activity, which...
NAD+ and the Hallmarks of Aging Series - Part 6...
These findings suggest that a conserved pathway may operate in mammals during calorie restriction involving the...
Why Too Much NMN or NR is Bad
High levels of NAM can have many negative effects such as inhibiting sirtuins, which is the opposite of what you are trying to accomplish by taking NAD+ boosters. The body...
Why Too Much NMN or NR is Bad
High levels of NAM can have many negative effects such as inhibiting sirtuins, which is the...
Reduced Nicotinamide Mononucleotide - A Tale of...
NAD+ Precursors and Healthy Aging Nicotinamide adenine dinucleotide (NAD+) is a coenzyme found in all living cells. It is a critical coenzyme for energy metabolism and also serves as the...
Reduced Nicotinamide Mononucleotide - A Tale of...
NAD+ Precursors and Healthy Aging Nicotinamide adenine dinucleotide (NAD+) is a coenzyme found in all living...
NAD+ and the Hallmarks of Aging Series - Part 5...
Overview Currently, available evidence strongly supports the idea that anabolic signaling (the signal that promotes growth and proliferation) accelerates aging, and decreased nutrient signaling extends longevity (Fontana et al., 2010)....
NAD+ and the Hallmarks of Aging Series - Part 5...
Overview Currently, available evidence strongly supports the idea that anabolic signaling (the signal that promotes growth...