Research

Senescent Cells: The Double-Edged Sword of Cell...
Although many signs of aging are easy to see, much of the process is actually driven by microscopic changes, which occur at a cellular level. Senescent cells are...
Senescent Cells: The Double-Edged Sword of Cell...
Although many signs of aging are easy to see, much of the process is...

Long Term NMN Use Extends Lifespan and Healthsp...
This study examined the effects of long-term NMN supplementation on lifespan, healthspan, and metabolic health in male and female mice. Key Points Increased median lifespan by 8.5% in female mice....
Long Term NMN Use Extends Lifespan and Healthsp...
This study examined the effects of long-term NMN supplementation on lifespan, healthspan, and metabolic health in...

Study Demonstrates Age Reversal through Cellula...
A team of scientists from Harvard Medical School discovered a method to distinguish young cells from old and senescent cells in real time. This allowed them to quickly screen the...
Study Demonstrates Age Reversal through Cellula...
A team of scientists from Harvard Medical School discovered a method to distinguish young cells from...

NR Shows Ability to Promote DNA Repair and Incr...
The ability to repair DNA damage decreases over time, causing an accumulation of mutations that can affect cellular function, viability, and an increase in the aging process. In a new...
NR Shows Ability to Promote DNA Repair and Incr...
The ability to repair DNA damage decreases over time, causing an accumulation of mutations that can...

NAD+ Reduces Mutations and Incidence of Skin Ca...
In a new study by Brown University School of Medicine, it was shown that oral nicotinamide (NAM) supplementation decreased the incidence of keratinocyte carcinoma (KC) in high-risk skin cancer patients....
NAD+ Reduces Mutations and Incidence of Skin Ca...
In a new study by Brown University School of Medicine, it was shown that oral nicotinamide...
Fisetin Effectively Eliminates Senescent Cells ...
Since immune cells play such a critical role in keeping the population of senescent cells in check, senescent immune cells are a prime target of senolytic drugs. Fisetin has been...
Fisetin Effectively Eliminates Senescent Cells ...
Since immune cells play such a critical role in keeping the population of senescent cells in...

Heart Disease Related to Accumulation of DNA Da...
As we age, the risk for clogged arteries, brittle blood vessels, and heart failure increase. A recent study looking at the DNA in numerous individual heart cells tells the story...
Heart Disease Related to Accumulation of DNA Da...
As we age, the risk for clogged arteries, brittle blood vessels, and heart failure increase. A...

David Sinclair's Supplement Stack and Longevity...
David Sinclair, a professor at Harvard University is perhaps the foremost expert in the growing field of longevity research. In a recent video, titled “Dr David Sinclair – Defeating Ageing...
David Sinclair's Supplement Stack and Longevity...
David Sinclair, a professor at Harvard University is perhaps the foremost expert in the growing field...

NAD+ and the Hallmarks of Aging Series – Part 8...
Altogether, these studies suggest that the decline of stem cell number and function is a hallmark of aging and is a major cause of decreased tissue homeostasis in the old...
NAD+ and the Hallmarks of Aging Series – Part 8...
Altogether, these studies suggest that the decline of stem cell number and function is a hallmark...

Trimethylglycine (TMG) for Restoring Methylatio...
TMG is a critical cofactor in methylation, which occurs in every mammalian cell donating methyl groups. This includes the synthesis of neurotransmitters such as serotonin and dopamine.
Trimethylglycine (TMG) for Restoring Methylatio...
TMG is a critical cofactor in methylation, which occurs in every mammalian cell donating methyl groups....

NAD+ and the Hallmarks of Aging Series - Part 5...
Growth Hormone and Insulin Growth hormone is a well-known hormone that promotes the growth and proliferation of cells. Its secondary mediator, insulin-like growth factor 1 (IGF-1), is produced in response...
NAD+ and the Hallmarks of Aging Series - Part 5...
Growth Hormone and Insulin Growth hormone is a well-known hormone that promotes the growth and proliferation...