LIPO Melatonin™ promotes high-quality sleep and balances your “body clock.”  Benefits may include improvement of sleep onset, sleep pattern and a decrease in cortisol levels.

Offering an advanced liposomal source of the natural hormone—N-acetyl-5-methoxytryptamine—LIPO Melatonin™ is expertly designed to overcome low absorption issues.

Balance Cortisol Levels

Melatonin is mainly known for its ability to regulate the sleep-wake cycle (circadian rhythm or chronobiology) via its release from the pineal gland.  Studies demonstrate that melatonin decreases sleep onset latency, increases total sleep time and improves overall sleep quality. 1

In addition to improving sleep, melatonin is also involved in managing immune function, blood pressure and cortisol levels. 2

Only 15% Absorption in Standard Melatonin Supplements

Oral melatonin has an absolute bioavailability of about 15 percent.  So, if you take a 4 mg melatonin pill, your body is only absorbing around 0.6 mg. 3

Our encapsulation process in liposomes protects melatonin from premature degradation while enhancing its intestinal absorption.

The absorption of non-liposomal oral melatonin is minimal due to high first-pass clearance in the liver and low absorption in the gastrointestinal tract. 4

Liposomes extend the time a supplement is available in the bloodstream, but the peak availability is between 2 and 4 hours, which is while you are sleeping.

However, some is absorbed well before the 2 hours and actually may work faster than standard Melatonin.

This study found Liposomal Melatonin decreased the time to sleep (Sleep latency – SL). from 18 minutes to 10 minutes.

“A significant difference in SL was observed (10.8 ± 5 vs. 18.1 ± 13.4 min, p-value = 0.002)… Our study confirmed the efficacy and safety of melatonin administration in sleep induction. Nonetheless, liposomal melatonin presents a greater bioavailability, ensuring a faster effect and allowing lower dosages.”